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Multiple small studies of CBD and its safety in humans (both in the U.S. and Israel) suggest it is well tolerated across a wide dosage range. No significant central nervous system side effects, or effects on vital signs or mood were seen at doses of up to 200mg/day by mouth (some suggest 600mg per day may be tolerable). However, the Cannabis Trades Association UK (non-Governmental) has no definite dosage suggestion but it does state that CBD products should have a recommended dosage on the bottle.